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Fumitake Gejyo Selected Research

Low Density Lipoprotein Receptor-Related Protein-2

5/2012Significance of urinary full-length and ectodomain forms of megalin in patients with type 2 diabetes.
10/2007Role of megalin, a proximal tubular endocytic receptor, in calcium and phosphate homeostasis.
1/2007Functional characterization of a novel missense CLCN5 mutation causing alterations in proximal tubular endocytic machinery in Dent's disease.
10/2005Role of megalin, a proximal tubular endocytic receptor, in the pathogenesis of diabetic and metabolic syndrome-related nephropathies: protein metabolic overload hypothesis.
6/2005Significance of proximal tubular metabolism of advanced glycation end products in kidney diseases.
4/2005Evidence for megalin-mediated proximal tubular uptake of L-FABP, a carrier of potentially nephrotoxic molecules.
1/2004Differentiation-induced cultured podocytes express endocytically active megalin, a heymann nephritis antigen.
8/2003Bioengineered implantation of megalin-expressing cells: a potential intracorporeal therapeutic model for uremic toxin protein clearance in renal failure.

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Fumitake Gejyo Research Topics

Disease

19Amyloidosis
02/2013 - 03/2003
17IGA Glomerulonephritis (IGA Nephropathy)
04/2012 - 12/2001
15Chronic Renal Insufficiency
01/2019 - 12/2004
15Proteinuria
09/2009 - 05/2002
14Infections
01/2012 - 10/2002
12Glomerulonephritis
04/2009 - 05/2002
11Secondary Hyperparathyroidism
03/2008 - 06/2003
10Asthma (Bronchial Asthma)
01/2012 - 09/2003
9Renal Insufficiency (Renal Failure)
01/2010 - 05/2000
8Hypertension (High Blood Pressure)
04/2014 - 05/2002
8Rheumatoid Arthritis
01/2012 - 01/2006
8Neoplasms (Cancer)
05/2010 - 08/2002
7Anemia
12/2016 - 03/2003
6Inflammation (Inflammations)
01/2018 - 05/2002
6Pneumonia (Pneumonitis)
04/2011 - 01/2002
6Nephritis
02/2011 - 12/2001
6Communicable Diseases (Infectious Diseases)
07/2007 - 10/2002
6Chronic Kidney Failure (Chronic Renal Failure)
01/2007 - 03/2002
6Respiratory Tract Infections (Respiratory Tract Infection)
10/2006 - 10/2002
5Arthralgia (Joint Pain)
01/2012 - 05/2003
5Systemic Lupus Erythematosus (Libman-Sacks Disease)
06/2009 - 03/2002
5T-Cell Leukemia (Leukemia, T Cell)
12/2006 - 03/2002
4Uremia
01/2018 - 03/2002
4Autoimmune Pancreatitis
01/2010 - 01/2006
4Fever (Fevers)
07/2009 - 05/2003
4Membranous Glomerulonephritis (Membranous Nephropathy)
12/2008 - 01/2004
4Mixed Connective Tissue Disease (MCTD)
01/2008 - 05/2002
4Hypoxia (Hypoxemia)
09/2007 - 07/2002
4Interstitial Lung Diseases (Interstitial Lung Disease)
07/2007 - 07/2002
4Vascular Diseases (Vascular Disease)
11/2003 - 05/2000
3Albuminuria
05/2012 - 02/2009
3Acute Lung Injury
11/2010 - 11/2006
3Kidney Diseases (Kidney Disease)
09/2009 - 06/2005
3Fibrosis (Cirrhosis)
11/2008 - 03/2007
3Lung Injury
09/2008 - 03/2007
3Periodontitis
12/2007 - 03/2003
3Lung Diseases (Lung Disease)
07/2007 - 04/2002
3Granulomatosis with Polyangiitis (Wegener's Granulomatosis)
11/2006 - 06/2003
3Takayasu Arteritis (Arteritis, Takayasu's)
11/2006 - 10/2002
3Carpal Tunnel Syndrome
08/2006 - 09/2002
3Hyperparathyroidism
08/2005 - 06/2003
3Disease Progression
09/2003 - 05/2002
2Pruritus (Itching)
01/2022 - 03/2008
2Type 2 Diabetes Mellitus (MODY)
05/2012 - 10/2005
2Hemorrhage
05/2012 - 02/2010
2Arthritis (Polyarthritis)
01/2012 - 03/2006
2Osteoporosis
12/2011 - 03/2003

Drug/Important Bio-Agent (IBA)

19Proteins (Proteins, Gene)FDA Link
01/2019 - 05/2002
10Amyloid (Amyloid Fibrils)IBA
02/2013 - 09/2002
10Prednisolone (Predate)FDA LinkGeneric
02/2010 - 10/2002
9Immunoglobulin G (IgG)IBA
04/2009 - 03/2003
8Low Density Lipoprotein Receptor-Related Protein-2IBA
05/2012 - 08/2003
7Hemoglobins (Hemoglobin)IBA
10/2014 - 03/2003
7Adrenal Cortex Hormones (Corticosteroids)IBA
01/2012 - 10/2002
7AntibodiesIBA
05/2010 - 10/2003
7Anti-Bacterial Agents (Antibiotics)IBA
07/2009 - 10/2002
7CytokinesIBA
12/2007 - 10/2002
6CreatinineIBA
04/2014 - 10/2006
5ErythropoietinFDA Link
12/2016 - 03/2003
5SteroidsIBA
07/2009 - 05/2002
5Pharmaceutical PreparationsIBA
01/2009 - 10/2002
5AntigensIBA
11/2008 - 04/2002
4HematinicsIBA
10/2014 - 03/2008
4EnzymesIBA
05/2012 - 03/2002
4AlbuminsIBA
05/2012 - 09/2008
4Immunoglobulin A (IgA)IBA
04/2012 - 04/2004
4antiglomerular basement membrane antibodyIBA
02/2011 - 03/2003
4DNA (Deoxyribonucleic Acid)IBA
01/2007 - 05/2002
4Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
06/2006 - 09/2003
4Angiotensin Receptor AntagonistsIBA
06/2006 - 09/2003
4Fibroblast Growth Factor-23IBA
08/2005 - 08/2004
3Uremic ToxinsIBA
01/2019 - 01/2018
3Phosphates (Orthophosphate)IBA
05/2012 - 06/2005
3Vitamin DFDA LinkGeneric
05/2012 - 06/2003
3AutoantibodiesIBA
02/2010 - 10/2004
3LipopolysaccharidesIBA
03/2009 - 11/2006
3nephrinIBA
11/2008 - 08/2003
3Calcitriol (Calcijex)FDA LinkGeneric
01/2008 - 03/2005
3Fc Receptors (Fc Receptor)IBA
12/2007 - 03/2003
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
09/2007 - 09/2005
3Messenger RNA (mRNA)IBA
01/2007 - 05/2005
3Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
11/2006 - 12/2001
3Fluticasone (Cutivate)FDA LinkGeneric
01/2006 - 11/2002
3GlycosaminoglycansIBA
11/2005 - 09/2003
3Proteoglycans (Proteoglycan)IBA
11/2005 - 09/2003
3Interleukin-2 (IL2)IBA
09/2005 - 07/2005
3maxacalcitolIBA
06/2005 - 06/2003
3Parathyroid Hormone (Parathormone)IBA
06/2005 - 03/2002
2Darbepoetin alfa (Aranesp)FDA Link
12/2012 - 02/2010
2ImmunosorbentsIBA
05/2012 - 03/2002
2Monoclonal AntibodiesIBA
05/2012 - 06/2006
2Biomarkers (Surrogate Marker)IBA
05/2012 - 01/2009
2Immunoglobulins (Immunoglobulin)IBA
01/2012 - 01/2005
2Oxygen (Dioxygen)IBA
04/2011 - 06/2007

Therapy/Procedure

34Therapeutics
01/2012 - 01/2002
18Renal Dialysis (Hemodialysis)
01/2022 - 09/2002
7Kidney Transplantation
07/2010 - 03/2003
4Drug Therapy (Chemotherapy)
01/2009 - 10/2003
3Tonsillectomy
12/2004 - 05/2003
2Hemoperfusion
02/2013 - 04/2004